McDevitt Group Patents - 176 total patents and patent applications in progress.

1. Chemically tailored corrosion resistant high-TC superconductor thin film structures and devices
   WO Publication No.: WO9611482
   Publication Date: 1996-04-18
   Authors: John. T. McDevitt, JI-Ping Zhuo, & Jianai Zhao
   Abstract: A corrosion resistant high temperature superconductor and a method of preparing said superconductors involving substitution of ions in the lattice to relieve stress and strain caused by mismatches bond lengths. Specific examples of such superconductors are Y1-yCayBa2-yLayCu3O7-d where O < y < 1.0 and O < d < 1 and YBa2-ySryCu3O7-d where O < y < 2 and O < d < 1. In YBa2Cu3O7-d structure, the internal stresses estimated from the difference between the bond valence sum and the formal oxidation state for Ba and Cu ions indicate that the Ba atom is too large for Cu-O cage at oxygen stoichiometric d = 0 and too small at d = 1. Therefore, the Ba (1.52 ANGSTROM ) is substituted by La (1.27 ANGSTROM ) and for keeping the same oxidation state of Cu as in the prototype material the Ca (1.12 ANGSTROM ) equivalent to La replaces the Y (1.019 ANGSTROM ). Various geometries for the stable superconductor formulations are described including monolithic bulk ceramic, encapsulated ceramic, monolithic film, encapsulated film and superlattice forms.
2. Chemically tailored corrosion resistant high-TC superconductor thin film structures and devices
   AU Publication No.: AU4130696
   Publication Date: 1996-05-02
   Authors: John. T. McDevitt, JI-Ping Zhuo, & Jianai Zhao
3. Chemically tailored corrosion resistant high-TC superconductors
   US Patent No.: US5591696
   Date Issued: 1997-01-07
   Authors: John. T. McDevitt, JI-Ping Zhuo, & Jianai Zhao
   Abstract: A corrosion resistant high temperature superconductor and a method of preparing said superconductors involving substitution of ions in the lattice to relieve stress and strain caused by mismatched bond lengths. Specific examples of such superconductors are Y1-yCayBa2-yLayCu3O7-d where O<y<1.0 and O<d<1 and YBa2-ySryCu3O7-d where 0<y<2 and O<d<1. In YBa2Cu3O7-d structure, the internal stresses estimated from the difference between the bond valence sum and the formal oxidation state for Ba and Cu ions indicate that the Ba atom is too large for Cu-O cage at oxygen stoichiometric d=0 and too small at d=1. Therefore, the Ba (1.52 ANGSTROM ) is substituted by La (1.27 ANGSTROM ) and for keeping the same oxidation state of Cu as in the prototype material the Ca (1.12 ANGSTROM ) equivalent to La replaces the Y (1.019 ANGSTROM )
4. Hybrid, dye antenna/thin film superconductor devices and methods of tuned photo-responsive control thereof
   US Patent No.: US5600172
   Date Issued: 1997-02-04
   Authors: John T. McDevitt & David C. Jurbergs
   Abstract: A surface of a thin film superconductor element is coated with a layer containing pre-selected dye, or multiple dyes, alone or in combination with intermediate reflective coatings (best mode), which, when maintained near Tc, upon exposure to a selected frequency of light acts as a narrow bandwidth absorber to change the resistive property of the underlying superconductor following energy transfer from the dye to the superconductor. The resistance change is electronically detectable to function as a wavelength selective high speed optoelectronic switch or sensor element. A plurality of elements can be arrayed with each element junction being sensitized by overcoating with a different dye layer, either alone or in combination with an underlying reflective coating, so that upon exposure to a broad spectrum or polychromic light source, the individual junctions will independently be switched or not depending on the wavelength to which the superconductor junction is tuned by the pre-selected dye, thereby permitting multiplexed photo-optical message transmission and detection. For example, a single optical fiber may carry several signals simultaneously, each of which is encoded in a different color ( lambda ) and transmitted as a polychromic beam. The array distinguishes between signals as each detector is tuned to a selected encoded light color.
5. Molecular level, precision control over the interfacial properties of high-TC superconductor structures and devices
   US Patent No.: US5846909
   Date Issued: 1998-12-08
   Authors: John T. McDevitt & Chad A. Mirkin
   Abstract: Use of monolayer films for the direct modification of high-Tc superconductor structures and devices. Methods for the formation of superconductor localized monolayer films have been discovered based on the spontaneous adsorption of molecules containing ligating functionalities, such as alkylamine, arylamine, and alkylthiol moieties. Molecules containing these types of functionalities are found to bind tenaciously to the metal ions which form the high-Tc superconductor surface. The derivatized superconductor structures can be prepared simply by soaking the high-Tc, superconductor structure or device in a dry organic solvent system which contains the derivatizing agent. Large changes in the superconductor interfacial properties can be achieved with such procedures allowing for the atomic level control of the surface properties of the superconductor. This discovery is particularly important to provide a) new methods to fabricate superconductor devices with atomic level precision, b) to form defect-free anti-corrosion layers, c) improved/optimized methods for lithographic processing of high-Tc devices, and d) improved adhesion of protective layers by surface-modification.
6. Sensor arrays for the measurement and identification of multiple analytes in solutions
   US Patent No.: US6680206
   Date Issued: 2004-01-20
   Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
   Dean P. Neikirk
   Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
7. Sensor arrays for the measurement and identification of multiple analytes in solutions
   WO Publication No.: WO0004372
   Publication Date: 2000-01-27
   Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
   Dean P. Neikirk
8. Sensor arrays for the measurement and identification of multiple analytes in solutions
   CA Publication No.: CA2337155
   Publication Date: 2000-01-27
   Authors: John T. McDevitt, Dean P. Neikirk, Eric V. Anslyn &
   Jason B. Shear
9. Sensor arrays for the measurement and identification of multiple analytes in solutions
   AU Publication No.: AU5316599
   Publication Date: 2000-02-07
   Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
   Dean P. Neikirk
10. Sensor arrays for the measurement and identification of multiple analytes in solutions
    EP Publication No.: EP1097369
    Publication Date: 2001-05-09
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
11. Method and system for remotely collecting and evaluating chemical/biochemical information
    WO Publication No.: WO0068670
    Publication Date: 2000-11-16
    Authors: Eric V. Anslyn, Sherry L. Acanfora-Florin, Damon Borich, James W. Douglas, John T. McDevitt, John A. McMorris III, Gregory A. Mullins, Dean B. Neikirk, Mike J. Otworth, John S. Scott &
    Jason B. Shear
    Abstract: The present invention provides a method and system for detecting analytes in a fluid sample in a system of interest. The method and system includes a sensor, which includes at least one reactant, having an integral detector. The detector detects spectroscopic changes of reactants as the fluid sample passes over the reactants. The spectroscopic changes are caused by an analyte present in the fluid sample interacting with reactants.
12. Method and system for remotely collecting and evaluating chemical/biochemical information
    AU Publication No.: AU4990500
    Publication Date: 2000-11-21
    Authors: Eric V. Anslyn, Sherry L. Acanfora-Florin, Damon Borich, James W. Douglas, John T. McDevitt, John A. McMorris III, Gregory A. Mullins, Dean B. Neikirk, Mike J. Otworth, John S. Scott &
    Jason B. Shear
13. Detection system based on an analyte reactive particle
    WO Publication No.: WO0106253
    Publication Date: 2001-01-25
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
14. Detection system based on an analyte reactive particle
    AU Publication No.: AU1325201
    Publication Date: 2001-02-05
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
15. Detection system based on an analyte reactive particle
    US Patent No.: US6602702
    Date Issued: 2003-08-05
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
16. General signaling protocols for chemical receptors in immobilized matrices
    WO Publication No.: WO0106244
    Publication Date: 2001-01-25
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
17. General signaling protocols for chemical receptors in immobilized matrices
    AU Publication No.: AU1429701
    Publication Date: 2003-07-08
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
18. General signaling protocols for chemical receptors in immobilized matrices
    US Patent No.: US6589779
    Date Issued: 2001-02-05
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
19. Method and apparatus for the delivery of samples to a chemical sensor array
    WO Publication No.: WO0106239
    Publication Date: 2001-01-25
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear,
    Dean P. Neikirk & Damon V. Borich
    Abstact: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
20. Method and apparatus for the delivery of samples to a chemical sensor array
    CA Publication No.: CA2379130
    Publication Date: 2001-01-25
    Authors: Damon V. Borich, John T. McDevitt, Eric V. Anslyn, Jason B. Shear & Dean P. Neikirk
21. Method and system for collecting and transmitting chemical information
    WO Publication No.: WO0155952
    Publication Date: 2000-01-31
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
22. Method and system for collecting and transmitting chemical information
    AU Publication No.: AU4719501
    Publication Date: 2001-08-07
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
23. Method and system for collecting and transmitting chemical information
    US Publication No.: US2003064422
    Publication Date: 2003-04-03
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
24. Jc in high magnetic field of bi-layer and multi-layer structures for high temperature superconductive materials
    US Patent No.: US6221812
    Date Issued: 2001-04-24
    Authors: Jiping Zhou, John T. McDevitt & John B. Goodenough
    Abstract: To improve the chemical stability, as well as the critical current density (JC) of a superconductive material in an external magnetic field, copper-oxide coating materials have been developed. In some embodiments, these coating materials include a composition with the formula R1-xCaxBa2-yLayCu3-zMzO7-delta, where R is a rare-earth element (e.g., La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, or Y), M is a transition metal (e.g., Mn, Re, Fe, Os, Co, Rh, Ir, Ni, Pd, Pt, Ag, Au, Zn, Cd, or Hg), 0<=x<=0.4, 0<=y<=0.4, and 0<=z<=1.0. These coating materials are preferably used as a surface layer on superconductive materials to impart corrosion resistance and an improved critical current density when the layers are exposed to magnetic fields
25. System for transferring fluid samples through a sensor array
    WO Publication No.: WO0155704
    Publication Date: 2001-08-02
    Authors: John T. McDevitt, Eric v. Anslyn, Jason B. Shear, Dean P. Neikirk & Young-Soo Sohn
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
26. System for transferring fluid samples through a sensor array
    AU Publication No.: AU3801101
    Publication Date: 2001-08-07
    Authors: John T. McDevitt, Eric v. Anslyn, Jason B. Shear, Dean P. Neikirk & Young-Soo Sohn
27. Method of preparing a sensor array
    WO Publication No.: WO0155703
    Publication Date: 2001-08-02
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
28. Method of preparing a sensor array
    AU Publication No.: AU3470901
    Publication Date: 2001-08-07
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
29. Method of preparing a sensor array
    US Patent No.: US6649403
    Date Issued: 2003-11-18
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
30. Portable sensor array system
    WO Publication No.: WO0155702
    Publication Date: 2001-08-02
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
31. Portable sensor array system
    AU Publication No.: AU3320001
    Publication Date: 2001-08-07
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
32. Portable sensor array system
    CA Publication No.: CA2401782
    Publication Date: 2001-08-02
    Authors: Dean P. Neikirk, Jason B. Shear, Eric V. Ansyln & John T. McDevitt
33. System and Method for analysis of bodily fluids
    WO Publication No.: WO0155701
    Publication Date: 2001-08-02
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a ligth source, a sensor array , and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using patten recognition techniques, the analytes within a multi-analyte fluid may be characterized.
34. System and Method for analysis of bodily fluids
    AU Publication No.: AU3659701
    Publication Date: 2001-08-07
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
35. Method and apparatus for the confinement of materials in a micromachined chemical sensor array
    US Publication No.: US2002197622
    Publication Date: 2002-12-26
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Byunghwa Park & Yoon Sok Park
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle. Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
36. Method and apparatus for the confinement of materials in a micromachined chemical sensor array
    WO Publication No.: WO02061392
    Publication Date: 2002-12-27
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Byunghwa
37. Method and apparatus for the confinement of materials in a micromachined chemical sensor array
    CA Publication No.: CA2437558
    Publication Date: 2002-08-08
    Authors: Jason B. Shear, Dean P. Neikirk, Byunghwa Park, Eric V. Anslyn, Yoon Sok Park & John T. McDevitt
38. Method and apparatus for the confinement of materials in a micromachined chemical sensor array
    EP Publication No.: EP1373874
    Publication Date: 2004-01-02
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Byunghwa Park & Yoon Sok Park
39. Method and apparatus for the confinement of materials in a micromachined chemical sensor array
    JP Publication No.: JP2004529323
    Publication Date: 2004-09-24
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Byunghwa Park & Yoon Sok Park
40. Magnetic-based placement and retention of sensor elements in a sensor array
    US Publication No.: US2002160363
    Publication Date: 2002-10-31
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
41. Magnetic-based placement and retention of sensor elements in a sensor array
    WO Publication No.: WO02103371
    Publication Date: 2002-12-27
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear & Dean P. Neikirk
42. Magnetic-based placement and retention of sensor elements in a sensor array
    AU Publication No.: AU2002330841
    Publication Date: 2003-01-02
    Authors: Eric V. Anslyn, Jason B. Shear, John T. McDevitt &
    Dean P. Neikirk
43. Method and system for the detection of cardiac risk
    WO Publication No.: WO03090605
    Publication Date: 2003-11-06
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, & Nick J. Christodoulides
    Abstract: A system for the rapid characterization of multi-cardiovascular risk factor analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle.; Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
44. Method and system for the detection of cardiac risk
    CA Publication No.: CA2523626
    Publication Date: 2003-11-06
    Authors: Dean P. Neikirk, John T. McDevitt, Nick J. Christodoulides,
    Eric V. Anslyn & Jason B. Shear
45. Method and system for the detection of cardiac risk
    EP Publication No.: EP1502097
    Publication Date: 2005-02-02
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk & Nick J. Christodoulides
46. Capture and detection of microbes by membrane methods
    WO Publication No.: WO2004009840
    Publication Date: 2004-01-29
    Authors: John T. McDevitt, Pierre Floriano, Nick J. Christodoulides, Adrian Goodey, Dean Neikirk, Eric Anslyn & Jason Shear
    Abstract: Methods and systems for detecting the presence of analytes using a membrane based detection system are described. A fluid sample is passed through a membrane based detection system (100). Particulate analytes (e.g., microbes) are captured by the membrane (110). Detection and analysis techniques may be applied to determine the identity and quantity of the captured analytes.
47. Capture and detection of microbes by membrane methods
    CA Publication No.: CA2494727
    Publication Date: 2004-01-29
    Authors: Dean Neikirk, Eric Anslyn, Jason Shear, Adrian Goodey, Nick J. Christodoulides, Pierre Floriano & John T. McDevitt
48. Capture and detection of microbes by membrane methods
    AU Publication No.: AU2003256742
    Publication Date: 2004-02-09
    Authors: Adrian Goodey, Dean Neikirk, Eric Anslyn, Jason Shear, John T. McDevitt, Pierre Floriano  & Nick J. Christodoulides
49. Capture and detection of microbes by membrane methods
    EP Publication No.: EP1546367
    Publication Date: 2005-06-29
    Authors: John T. McDevitt, Pierre Floriano, Nick J. Christodoulides, Adrian Goodey, Dean Neikirk, Eric Anslyn & Jason Shear
50. Capture and detection of microbes by membrane methods
    JP Publication No.: JP2005533502
    Publication Date: 2005-11-10
    Authors: John T. McDevitt, Pierre Floriano, Nick J. Christodoulides, Adrian Goodey, Dean Neikirk, Eric Anslyn & Jason Shear
51. Capture and detection of microbes by membrane methods
    US Publication No.: US2006073585
    Publication Date: 2006-04-06
    Authors: John T. McDevitt, Pierre Floriano & Nick J. Christodoulides
52. Capture and detection of microbes by membrane methods
    US Publication No.: US2006079000
    Publication Date: 2006-04-13
    Authors: Pierre Floriano, John T. McDevitt & Nick J. Christodoulides
53. Capture and detection of microbes by membrane methods
    ZA Patent No.: ZA200500889
    Date Issued: 2006-07-26
    Authors: John T. McDevitt, Pierre Floriano, Nick J. Christodoulides, Adrian Goodey, Dean Neikirk, Eric Anslyn & Jason Shear
54. Method and system for the detection of cardiac risk factors
    US Publication No.: US2004029259
    Publication Date: 2004-02-12
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk & Nick J. Christodoulides
    Abstract: A system for the rapid characterization of multi-cardiovascular risk factor analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle. Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
55. Sensor arrays for the measurement and identification of multiple analytes in solutions
    AU Publication No.: AU770949
    Publication Date: 2004-03-11
    Authors: Eric V. Anslyn, Jason B. Shear, John T. McDevitt &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavitites may be formed. A series of chemically sensitive particles microspheres are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
56. System and method for the analysis of bodily fluids
    US Publication No.: 2004053322
    Publication Date: 2004-03-18
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
57. System and method for the analysis of bodily fluids
    US Publication No.: US2005136548
    Publication Date: 2005-06-23
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
58. Method and apparatus for the delivery of samples to a chemical sensor array
    US Patent No.: 6713298
    Date Issued: 2004-03-30
    Authors: Eric V. Anslyn, Jason B. Shear, John T. McDevitt &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
59. Method and apparatus for the delivery of samples to a chemical sensor array
    AU Patent No.: AU773679
    Date Issued: 2004-06-03
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
60. A microchip-based system for HIV diagnostics
    WO Publication No.: WO2004072097
    Publication Date: 2004-08-26
    Authors: Bruce D. Walker, William R. Rodriguez & John T. McDevitt
    Abstract: The invention relates to microchip-based assays to measure HIV-associated analytes of interest (e.g., CD4 lymphocytes, HIV RNA and liver enzymes) in a sample from a subject infected with the HIV virus. Methods of the present invention are optimal for use in monitoring HIV disease in resource-poor settings.
61. A microchip-based system for HIV diagnostics
    CA Publication No.: CA2515348
    Publication Date: 2004-08-26
    Authors: John T. McDevitt, Bruce D. Walker, William R. Rodriguez, Nick J. Christodoulides & Pierre Floriano
62. A microchip-based system for HIV diagnostics
    AU Publication No.: AU2004212464
    Publication Date: 2004-08-26
    Authors: Bruce D. Walker, William R. Rodriguez & John T. McDevitt
63. A microchip-based system for HIV diagnostics
    JP Publication No.: JP2006516743
    Publication Date: 2006-07-06
    Authors: Bruce D. Walker, William R. Rodriguez & John T. McDevitt
64. A microchip-based system for HIV diagnostics
    BRP Publication No.: BRP10407299
    Publication Date: 2006-02-07
    Authors: Bruce D. Walker, William R. Rodriguez, John T. McDevitt, Pierre Floriano & Nick J. Christodoulides
65. A microchip-based system for HIV diagnostics
    US Publication No.: US2006234209
    Publication Date: 2006-10-19
    Authors: Bruce D. Walker, William R. Rodriguez, John T. McDevitt
66. Multi-shell microspheres with integrated chromatographic and detection layers for use in array sensors
    WO Publication No.: WO2004072613
    Publication Date: 2004-08-26
    Authors: John T. McDevitt, Adrian Goodey, Eric V. Anslyn, Jason B. Shear & Dean P. Neikirk
    Abstract: The development of miniaturized chromatographic systems localized within individual polymer microspheres and their incorporation into a bead-based cross-reactive sensor array platform is described herein. The integrated chromatographic and detection concept is based on the creation of distinct functional layers within the microspheres. In this first example of the new methodology, complexing ligands have been selectively immobilized to create "separation" layers harboring an affinity for various analytes. Information concerning the identities and concentrations of analytes may be drawn from the temporal properties of the beads' optical responses. Varying the nature of the ligand in the separation shell yields a collection of cross-reactive sensing elements well suited for use in array-based micro-total-analysis systems.
67. Multi-shell microspheres with integrated chromatographic and detection layers for use in array sensors
    CA Publication No.: CA2515305
    Publication Date: 2004-08-26
    Authors: John T. McDevitt, Adrian Goodey, Jason B. Shear, Dean P. Neikirk & Eric V. Anslyn
68. Multi-shell microspheres with integrated chromatographic and detection layers for use in array sensors
    EP Publication No.: EP1590659
    Publication Date: 2005-11-02
    Authors: John T. McDevitt, Adrian Goodey, Eric V. Anslyn, Jason B. Shear & Dean P. Neikirk
69. Multi-shell microspheres with integrated chromatographic and detection layers for use in array sensors
    ZA Publication No.: ZA200506560
    Publication Date: 2006-05-31
    Authors: John T. McDevitt, Adrian Goodey, Eric V. Anslyn, Jason B. Shear & Dean P. Neikirk
70. Multi-shell microspheres with integrated chromatographic and detection layers for use in array sensors
    US Publication No.: US2006228256
    Publication Date: 2006-10-12
    Authors: John T. McDevitt, Adrian Goodey, Eric V. Anslyn, Jason B. Shear & Dean P. Neikirk
71. Fluid based analysis of multiple analytes by a sensor array
    US Patent No.: US6908770
    Date Issued: 2005-06-21
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
    Dean P. Neikirk
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
72. Method and system for the analysis of saliva using a sensor array
    WO Publication No.: WO2005059551
    Publication Date: 2005-06-30
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk & Nick J. Christodoulides
    Abstract: A system for the rapid characterization of analytes in saliva. In one embodiment, a system for detecting analytes includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle.; Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
73. Method and system for the analysis of saliva using a sensor array
    CA Publication No.: CA2549190
    Publication Date: 2005-06-30
    Authors: Jason B. Shear, Eric V. Anslyn, John T. McDevitt, Nick J. Christodoulides & Dean P. Neikirk
74. Method and system for the analysis of saliva using a sensor array
    AU Publication No.: AU2004300168
    Publication Date: 2005-06-30
    Authors: Nick J. Christodoulides, Jason B. Shear, John T. McDevitt, Dean P. Neikirk & Eric V. Anslyn
75. Method and system for the analysis of saliva using a sensor array
    EP Publication No.: EP1695082
    Publication Date: 2006-08-30
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk & Nick J. Christodoulides
76. Particle on membrane assay system
    US Publication No.: US2005191620
    Publication Date: 2005-09-01
    Authors: John T. McDevitt, Nick Christodoulides, Pierre Floriano, Karri L. Ballard & Bruce Bernard
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
77. Particle on membrane assay system
    WO Publication No.: WO2005085854
    Publication Date: 2005-09-15
    Authors: John T. McDevitt, Nick Christodoulides, Pierre Floriano, Karri L. Michael-Ballard & Bruce Bernard
78. Particle on membrane assay system
    CA Publication No.: CA2557563
    Publication Date: 2005-09-15
    Authors: Pierre Floriano, Karri L. Michael-Ballard John T. McDevitt, Nick Christodoulides, & Bruce Bernard
79. Particle on membrane assay system
    EP Publication No.: EP1723420
    Publication Date: 2006-11-22
    Authors: John T. McDevitt, Nick Christodoulides, Pierre Floriano, Karri L. Michael-Ballard & Bruce Bernard
80. System and method for integrating fluids and reagents in self-contained cartridges containing particle and membrane sensor elements
    WO Publication No.: WO2005083423
    Publication Date: 2005-09-09
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Nick J. Christodoulides, Karri L. Michael-Ballard & Pierre Floriano
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
81. System and method for integrating fluids and reagents in self-contained cartridges containing particle and membrane sensor elements
    CA Publication No.: CA2557549
    Publication Date: 2005-09-09
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Nick J. Christodoulides, Karri L. Michael-Ballard, Pierre Floriano &
    Dean P. Neikirk
82. System and method for integrating fluids and reagents in self-contained cartridges containing particle and membrane sensor elements
    EP Publication No.: EP1735618
    Publication Date: 2006-12-27
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Nick J. Christodoulides, Karri L. Michael-Ballard, Pierre Floriano &  Bruce Bernard
83. System and method for integrating fluids and reagents in self-contained cartridges containing sensor elements and reagent delivery systems
    WO Publication No.: WO2005085855
    Publication Date: 2005-09-15
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Nick J. Christodoulides, Pierre Floriano &
    Karri L. Michael-Ballard
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
84. System and method for integrating fluids and reagents in self-contained cartridges containing sensor elements and reagent delivery systems
    US Publication No.: US2006257992
    Publication Date: 2006-11-16
    Authors: John T. McDevitt, Karri L. Michael-Ballard, Pierre Floriano, Nick J. Christodoulides, Dean P. Neikirk, Eric V. Anslyn &
    Jason B. Shear
85. System and method for integrating fluids and reagents in self-contained cartridges containing sensor elements
    WO Publication No.: WO2005085796
    Publication Date: 2005-09-15
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Nick J. Christodoulides, Karri L. Michael-Ballard &
    Pierre Floriano
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
86. Membrane assay system including preloaded particles
    WO Publication No.: WO2005090983
    Publication Date: 2005-09-29
    Authors: John T. McDevitt, Nick Christodoulides, Pierre Floriano, Karri L. Michael-Ballard & Bruce Bernard
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
87. Membrane assay system including preloaded particles
    US Publication No.: WO2006257854
    Publication Date: 2006-11-16
    Authors: John T. McDevitt, Nick Christodoulides, Pierre Floriano, Karri L. Michael-Ballard & Bruce Bernard
88. Method and apparatus for the delivery of samples to a chemical sensor array
    US Patent No.: US7022517
    Date Issued: 2006-04-04
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk & Damon V. Borich
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
89. Capture and detection of microbes by membrane methods
    BRP Publication No.: BRPI0501090
    Publication Date: 2006-10-03
    Authors: John T. McDevitt, Pierre Floriano, Nick J. Christodoulides, Adrian Goodey, Dean Neikirk, Eric Anslyn & Jason Shear
    Abstract: Abstract: Methods and systems for detecting the presence of analytes using a membrane based detection system are described. A fluid sample is passed through a membrane based detection system (100). Particulate analytes (e.g., microbes) are captured by the membrane (110). Detection and analysis techniques may be applied to determine the identity and quantity of the captured analytes.
90. Integration of fluids and reagents into self-contained cartridges containing particle and membrane sensor elements
    US Publication No.: US2006257941
    Publication Date: 2006-11-16
    Authors: John T. McDevitt, Karri L. Michael-Ballard, Pierre Floriano, Nick J. Christodoulides, Dean P. Neikirk, Eric V. Anslyn &
    Jason B. Shear
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
91. Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
    US Publication No.: US2006257991
    Publication Date: 2006-11-16
    Authors: John T. McDevitt, Karri L. Michael-Ballard, Pierre Floriano, Nick J. Christodoulides, Dean P. Neikirk, Eric V. Anslyn &
    Jason B. Shear
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
92. Integration of fluids and reagents into self-contained cartridges containing sensor elements
    US Publication No.: US2006257993
    Publication Date: 2006-11-16
    Authors: John T. McDevitt, Karri L. Michael-Ballard, Pierre Floriano, Nick J. Christodoulides, Dean P. Neikirk, Eric V. Anslyn &
    Jason B. Shear
    Abstract: Described herein is an analyte detection device and method related to a portable instrument suitable for point-of-care analyses. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular- and/or particle-based analyses and may be used in conjunction with membrane- and/or particle-based analysis cartridges. Analytes, including proteins and cells and/or microbes may be detected using the membrane and/or particle based analysis system.
93. Method and apparatus for delivery of samples to a chemical sensor array
    EP Patent No.: EP1204859
    Date Issued: 2006-11-22
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk & Damon V. Borich
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
94. Method and apparatus for delivery of samples to a chemical sensor array
    AT Publication No.: AT346287
    Publication Date: 2006-12-15
    Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk & Damon V. Borich
95. Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
    CA Publication No.: CA2613078
    Publication Date: 2007-01-04
    Authors: Glennon W. Simmons, Pierre N. Floriano, Nicolaos J. Christodoulides, Karri Ballard & John T. McDevitt
    Abstract: Methods, systems, and apparatus for detecting the presence of analytes are described. A fluid or gas sample may pass through a microsieve-based detecti on system and/or a particle- based detection system of a cartridge. Detection a nd analysis techniques may be applied to determine the identity and quantity of the captured analytes.
96. Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
    AU Publication No.: AU2006261953
    Publication Date: 2007-01-04
    Authors: Pierre N. Floriano, Karri Ballard, Nicolaos J. Christodoulides, Glennon W. Simmons & John T. McDevitt
97. Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
    WO Publication No.: WO2007002480
    Publication Date: 2007-01-04
    Authors: John T. McDevitt, Karri Ballard, Nicolaos J. Christodoulides & Pierre N. Floriano, Glennon W. Simmons
98. Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
    EP Publication No.: EP1899450
    Publication Date: 2008-03-19
    Authors: John T. McDevitt, Karri Ballard, Nicolaos J. Christodoulides & Pierre N. Floriano,  Glennon W. Simmons
99. Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
    ZA Publication No.: ZA200800413
    Publication Date: 2009-07-29
    Authors: John T. McDevitt, Nicolaos J. Christodoulides, Glennon W. Simmons Karri Ballard & Pierre N. Floriano
100. System and method of analyte detection using differential receptors
     WO Publication No.: WO2007005666
     Publication Date: 2007-01-11
     Authors: Eric V. Anslyn, John T. McDevitt, Jason B. Shear, Dean P. Neikirk, Aaron T. Wright & Zhenlin Zhong
     Abstract: Methods and systems for detecting the presence of analytes are described. A fluid or gas sample containing one or more analytes may pass through a particle-based sensor array. Detection and analysis techniques may be applied to determine the identity and quantity of the analytes.
101. System and method of analyte detection using differential receptors
     US Publication No.: US2009215646
     Publication Date: 2009-08-27
     Authors: Eric V. Anslyn, John T. McDevitt, Jason B. Shear, Dean P. Neikirk, Aaron T. Wright & Zhenlin Zhong
102. Methods and compositions related to determination and use of white blood cell counts
     WO Publication No.: WO2007053186
     Publication Date: 2007-05-10
     Authors: John T. McDevitt, Nicolaos J. Christodoulides, Pierre N. Floriano, Gary N. Douglas & Patrick E. Rogers
     Abstract: Described herein are methods and compositions for analyte detection with a portable instrument suitable for point-of-care analyses wherein the device may be used for a differential assay of blood components, such as lymphocyte populations or other cell populations, which can be used in diagnosis, and for monitoring treatment of diseases, such as HIV infection. In some embodiments, a portable instrument may include a disposable cartridge, an optical detector, a sample collection device and/or sample reservoir, reagent delivery systems, fluid delivery systems, one or more channels, and/or waste reservoirs. Use of a portable instrument may reduce the hazard to an operator by reducing an operator's contact with a sample for analysis. The device is capable of obtaining diagnostic information using cellular-based analyses in conjunction with microsieve-based analysis cartridges.
103. Methods and compositions related to determination and use of white blood cell counts
     AU Publication No.: AU2006309284
     Publication Date: 2007-05-10
     Authors: Pierre N. Floriano, John T. McDevitt, Nicolaos J. Christodoulides, Gary N. Douglas & Patrick E. Rogers
104. Methods and compositions related to determination and use of white blood cell counts
     CA Publication No.: CA2610793
     Publication Date: 2007-05-10
     Authors: John T. McDevitt, Nicolaos J. Christodoulides, Pierre N. Floriano, Gary N. Douglas & Patrick E. Rogers
105. Methods and compositions related to determination and use of white blood cell counts
     EP Publication No.: EP1910824
     Publication Date: 2008-04-16
     Authors: John T. McDevitt, Nicolaos J. Christodoulides, Pierre N. Floriano, Gary N. Douglas & Patrick E. Rogers
106. Methods and compositions related to determination and use of white blood cell counts
     US Publication No.: US2009215072
     Publication Date: 2009-08-27
     Authors: John T. McDevitt, Nicolaos J. Christodoulides, Pierre N. Floriano, Gary N. Douglas & Patrick E. Rogers
107. A method and apparatus for the delivery of samples to a chemical sensor array
     DE Publication No.: DE60031988
     Publication Date: 2007-06-14
     Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk & Damon V. Borich
     Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
108. Detecting tumor biomarker in oral cancer
     WO Publication No.: WO2007134189
     Publication Date: 2007-11-22
     Authors: Shannon Weigum, Pierre N. Floriano, Nicolaos Christodoulides & John T. McDevitt
     Abstract: Methods and device for detecting the presence of tumor biomarkers in oral squamous cell carcinoma. A membrane based cell capture device allows deliver of cell samples and reagents to the membrane.
109. Detecting tumor biomarker in oral cancer
     US Publication No.: US2008038738
     Publication Date: 2008-02-14
     Authors: Shannon Weigum, Pierre N. Floriano, Nicolaos Christodoulides & John T. McDevitt
110. Detecting tumor biomarker in oral cancer
     EP Publication No.: EP2021491
     Publication Date: 2009-02-11
     Authors: Shannon Weigum, Pierre N. Floriano, Nicolaos Christodoulides & John T. McDevitt
111. Detecting multiple types of leukocytes
     WO Publication No.: WO2007134191
     Publication Date: 2007-11-22
     Authors: Pierre N. Floriano, Nicolaos Christodoulides, Karri Ballard & John T. McDevitt
     Abstract: Methods, systems, and apparatus for detecting multiple types of leukocytes in a blood sample material. A fluid or gas sample may pass through a sieve-based detection system of a cartridge. Detection and analysis techniques may be applied to determine the relative distribution of multiple types of white blood cells in the sample.
112. Detecting multiple types of leukocytes
     CA Publication No.: CA2651872
     Publication Date: 2007-11-22
     Authors: Nicolaos Christodoulides, Karri Ballard, Pierre N. Floriano & John T. McDevitt
113. Detecting multiple types of leukocytes
     US Publication No.: US2008050830
     Publication Date: 2008-02-28
     Authors: Pierre N. Floriano, Nicolaos Christodoulides, Karri Ballard & John T. McDevitt
114. Detecting multiple types of leukocytes
     EP Publication No.: EP2027249
     Publication Date: 2009-02-25
     Authors: Pierre N. Floriano, Nicolaos Christodoulides, Karri Ballard & John T. McDevitt
115. Portable sensor array system
     US Patent No.: US7316899
     Date Issued: 2008-01-08
     Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
     Dean P. Neikirk
     Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
116. Portable sensor array system
     EP Patent No.: EP1255980
     Date Issued: 2008-06-30
     Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
     Dean P. Neikirk
117. Portable sensor array system
     US Publication No.: US2008219891
     Publication Date: 2008-09-11
     Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
     Dean P. Neikirk
118. Detecting human or animal immunoglobin-E
     US Publication No.: US2008176253
     Publication Date: 2008-07-24
     Authors: Nicolaos Christodoulides, Pierre N. Floriano, Karri Ballard & John T. McDevitt
     Abstract: Methods, systems, and apparatus for detecting the presence of human or animal immunoglobin-E are described. A fluid or gas sample may pass through a particle-based detection system of a cartridge. Detection and analysis techniques may be applied to determine the identity and quantity of the captured IgE.
119. System for transferring fluid samples through a sensor array
     AT Publication No.: AT403145
     Publication Date: 2008-08-15
     Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
     Dean P. Neikirk
     Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
120. Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics
     WO Publication No.: WO2008131039
     Publication Date: 2008-10-30
     Authors: John T. McDevitt, Nicolaos Christodoulides, Jeff Ebersole, Craig S. Miller & Pierre Floriano
     Abstract: Embodiments of the invention include methods by which cardiac biomarkers are assigned an index (cardiovascular biomarker index-cardiobioindex, CBI) as a means to describe the utility of each biomarker, or combination of biomarkers for risk evaluation, diagnosis or prognosis of cardiovascular disease status.
121. Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics
     CA Publication No.: CA2697357
     Publication Date: 2008-10-30
     Authors: John T. McDevitt, Nicolaos Christodoulides, Jeff Ebersole, Craig S. Miller & Pierre Floriano
122. Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics
     US Publication No.: US2008300798
     Publication Date: 2008-12-04
     Authors: John T. McDevitt, Nicolaos Christodoulides, Pierre Floriano, Craig S. Miller & Jeff Ebersole
123. Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics
     EP Publication No.: EP2147115
     Publication Date: 2010-01-27
     Authors: John T. McDevitt, Nicolaos Christodoulides, Jeff Ebersole, Craig S. Miller & Pierre Floriano
124. Fluid based analysis of multiple analytes by a sensor array
     US Patent No.: US7491552
     Date Issued: 2009-02-17
     Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
     Dean P. Neikirk
     Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
125. Fluid based analysis of multiple analytes by a sensor array
     US Publication No.: US2009258791
     Publication Date: 2009-10-15
     Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear &
     Dean P. Neikirk
126. Capture and detection of microbes by membrane methods
     IN Patent No.: IN231681
     Date Issued: 2009-03-07
     Authors: John T. McDevitt, Pierre Floriano & Nick J. Christodoulides
     Abstract: Methods and systems for detecting the presence of analytes using a membrane based detection system are described. A fluid sample is passed through a membrane based detection system (100). Particulate analytes (e.g., microbes) are captured by the membrane (110). Detection and analysis techniques may be applied to determine the identity and quantity of the captured analytes.
127. Capture and detection of microbes by membrane methods
     EP Publication No.: EP2107120
     Publication Date: 2009-10-07
     Authors: John T. McDevitt, Pierre Floriano & Nick J. Christodoulides
128. Method and system for the detection of cardiac risk factors
     AU Publication No.: AU2009202457
     Publication Date: 2009-07-16
     Authors: Dean P. Neikirk, Eric V. Anslyn, Nicolaos Christodoulides, Jason B. Shear & John T. McDevitt
     Abstract: A system for the rapid characterization of multi-cardiovascular risk factor analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle.; Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
129. Method and system for the detection of cardiac risk factors
     AU Patent No.: AU2003228711
     Date Issued: 2009-07-16
     Authors: Jason B. Shear, Nick J. Christodoulides, John T. McDevitt, Eric V. Anslyn & Dean P. Neikirk
130. A microchip-based system for HIV diagnostics
     EP Patent No.: EP1590669
     Date Issued: 2009-11-25
     Authors: Bruce Walker, William Rodriguez, John T. McDevitt & Nick J. Christodoulides
     Abstract: The invention relates to microchip-based assays to measure HIV-associated analytes of interest (e.g., CD4 lymphocytes, HIV RNA and liver enzymes) in a sample from a subject infected with the HIV virus. Methods of the present invention are optimal for use in monitoring HIV disease in resource-poor settings.
131. A microchip-based system for HIV diagnostics
     AT Publication No.: AT449962
     Publication Date: 2009-12-15
     Authors: Bruce Walker, William Rodriguez, John T. McDevitt & Nick J. Christodoulides
132. A microchip-based system for HIV diagnostics
     DE Publication No.: DE602004024285
     Publication Date: 2010-01-07
     Authors: Bruce Walker, William Rodriguez, John T. McDevitt & Nick J. Christodoulides
133. Method and system for the analysis of saliva using
     a sensor array
     US Patent No.: 7651868
     Date Issued: 2010-01-26
     Authors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk & Nick J. Christodoulides
     Abstract: A system for the rapid characterization of analytes in saliva. In one embodiment, a system for detecting analytes includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle.; Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.